BIOL 11022

>< Type/Status : Compulsory for biological science students
>< Course title : Genetics
>< Prerequisite : G. C. E. (A/ L) BIOLOGY
>< Objective: At the completion of the course, the student will be able to
(i) demonstrate knowledge and conceptual understanding of the principles of inheritance and fundamentals of molecular and human genetics, and
(ii) apply this knowledge in solving basic problems within the context of genetics.
>< Course content:

Extensions of Mendellian pattern of inheritance. Linkage and chromosome mapping. Genetic basis of sex determination. Sex-linked inheritance. Molecular organization of genetic material. Replication of DNA. Gene function: Introduction to prokaryotic gene expression: Transcription and genetic aspects of translation. Mutations. Genetic variations at population level and their effects on gene pool. Human genome. Molecular basis of common human genetic diseases.

>< Methodology: Lectures and laboratory exercises.
>< Scheme of evaluation: End of course written examination
>< Recommended reading:
1. Griffiths, A. J. F., Miller, J. H., Suzuki, D.T. and Gelbart W. M. (1996). An Introduction to Genetic Analysis. 6th Edition. W H Freeman.
2. Fristrom, J. W. and Clegg, M. T. (1988). Principles of Genetics. 2nd Edition. W H Freeman.
3. Synder, L. and Champness, W. (1997). Molecular Genetics of Bacteria. American Society for Microbiology.

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