MIBI 43056

>< Type/Status : Compulsory
>< Title : Medical Microbiology and Immunology
>< Pre-requisite : All MIBI core course units of the B. Sc. General Degree programme
>< Objectives : At the end of the course unit, the students will be able to demonstrate the knowledge and understanding of
• the main features of the non-specific Immune system which present barriers to infection,
• the key features of the specific immune system,
• the general functions of specific & non-specific Immune systems,
• understand the principles & methods of diagnostic Immunology.
• demonstrate the understanding if aetiology & laboratory diagnosis techniques of infectious diseases affecting various body systems.
• dmonstrate the understanding of the important clinical features and control.
>< Course content :

Medical Microbiology
Host parasite relationships; pathogenicity; Defense mechanisms in human body. Infectious diseases affecting the various body systems with reference to their aetiology, clinical features, laboratory diagnosis and control. A detailed consideration of one infectious disease, that will be used to illustrate general principles applicable to the diseases of the same group. Anatomy and physiology of the sites concerned will also be reviewed briefly.
Diseases of skin and superficial tissues. Respiratory tract, urinogenital tract, mouth, ears and eyes infections. Infections of the central nervous system. Some common viral and protozoan diseases. Epidemiology and control of infectious diseases, control of sources and spread of infection by vaccination, antibiotics and the problems arising form their misuse (non-clinical uses of antibiotics). Mechanisms of antimicrobial action and drug resistance.

Immunology:
Introduction to immunology. Inflammation and phagocyte function. Lymphocytes in immune response. Immunoglobulin structure and function. The complement system. Antigens, receptors, and recognition. Microbial antigens; Diagnostic serology and serotaxonomy. Immunochemical techniques. The major histocompatability complex. The modulation of immune response.

>< Methodology: Throughout the year course with a combination oflectures and tutorials.
>< Scheme of Evaluation: 100% end of course examination.
>< Recommended Reading:
1. Turgeon, M.L (1995) Immunology and serology in laboratory.2nd ed. Plenum. Press, NewYork.
2. Atlas, R M (1996). Microbiology Fundamentals and applications. Wm. C. Brown Publishers
3. Tortora, G.J.; Funke, B.R.; Case, C.L (1998) Microbiology. Benjamin Cummings Publishers, Addison Wesley Longman, Inc.

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