CHEM 43114

>< Type/Status : Compulsory
>< Title : Advanced Organic Chemistry II
>< Objectives : To provide current developments in organic synthesis and natural products chemistry.
>< Course Content :

Synthetic Organic Chemistry

Synthons in the synthesis of carbon chains and carbocycles, organo S, Si, B and P reagents, organometallic reagents, oxidation and reduction reactions, protection of functional groups, asymmetric synthesis, retrosynthestic analysis and target molecule synthesis.

Carbohydrates

Conformations and reactions of monosaccharides and their derivatives (amino, deoxy, branched chain, thio and unsaturated sugars); structure and synthesis of disaccharides, industrial importance of carbohydrates.

Natural Products

Chemistry and biosynthesis of selected examples from terpenes steroids and alkaloids. Biosynthesis of natural products (polyketide pathway, shikimic acid pathway and phenyl propanoids).

Supramolecular Chemistry

Molecular receptors and recognition, supramolecular reactivity and catalysis crown ethers and cyclodextrins.

>< Process : A combination of lectures and tutorial discussions.
>< Scheme of Evaluation : 100% end of course examination.
>< Recommended Reading :
1. Bindara, J. S. and Bindara, R. (1975), Creativity in Organic Synthesis, Vol. 1, Academic.
2. Mann, J. (1987), Secondary metabolism, 2nd edition, Oxford.
3. Robyt, J. F. (1998), Essentials of Carbohydrate Chemistry, Springer.
4. Carruthers, W. (1996), Modern Aspects of Organic Synthesis, 3rd edition, Cambridge.
5. Torssell, K. B. G. (1997), Natural product Chemistry, 2nd edition, Apote.
6. Carey, F. A. and Sundberg, R. J. (2000), Advanced Organic Chemistry, Part B, 4th edition, Plenum.
7. Nograchi, M. (1987), Stereoselective synthesis, VCH.
8. Fuhrhop, J and Panzlin, G. (1987), Organic synthesis, concepts, Methods, stating Materials, VCH.

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