CHEM 43124

>< Type/Status : Compulsory
>< Title : Biochemistry II
>< Objectives : To provide applications of biochemistry areas.
>< Course Content :

Applied Biochemistry
Recombinant DNA technology, tools in molecular cloning, Application of PCR, molecular probes, Medical, agricultural and industrial biotechnology.

Immunochemistry
Cells of immune system, innate immunity, immunogens & immunoglobulins, tissue transplantation, immunohaematology and immunoassays.

Neurobiochemistry
Biochemistry of excitatory and inhibitory neurotransmitters, effects of toxins, drugs hormones and growth factors on the nervous system.

Food Biochemistry
Nature and properties of biomelecules in food and food Processing, analytical methods used in analysis of food, natural occurring toxins, toxin formation during Processing, detection of nutritional quality of food, G.M. foods and food laws and regulations.

Medicinal Chemistry
Drug discovery, Systematic drug development, Pharmacodynamics, Pharmacokinetics, QSAR, Modern therapeutics, Impact of molecular biology & molecular modeling in drug discovery, Traditional medicines and their quality assurance, drugs derived from botanicals and aromatherapy.

>< Process : A combination of lectures and tutorial discussions
>< Scheme of Evaluation : 100% end of course examination
>< Recommended Reading :
1. Voet, D. and Voet, J. G. (1995), Biochemistry, John Willey.
2. Vanholde, M. (1990), Biochemistry, Benjamin.
3. Potter, N. N. and Hotchkiss, J. H. (1997), Food Science, Aspen.
4. Johnstone, A. P. and Turner, M. W. (1997), Immunochemistry, Oxford.
5. Stryer, L. (1995), Biochemistry, 4th edition, Freeman.
6. Lehninger, L., Nelson, D. L. and Cox, M. M. (1993), Principles of Biochemistry, Worth.
7. Siegel, G. J. Agranoff, B. W., Alber, R. W. and Molinoff, P. B. (1993), Neurochemistry, Reven.
8. Sammes, P. G. (1990), Comprehensive Medicinal Chemistry, Pergmon.
9. Silverman, R. (1992), The organic chemistry of drug design and drug action, Academic.
10. Patrick, G. L. (1998), An introduction to medicinal chemistry, Oxford.

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