MBBT 43083

>< Type/Status : Compulsory
>< Course title : Computer Applications in Molecular Biology and Biotechnology
>< Objectives: Having completed the course, the student will develop skills in data handling and interpretation for manipulation and analysis of nucleotide and amino acid sequences, and use of sources of bioinformation.
>< Course content:

Analysis of DNA sequences to search for open-reading frames, promoter regions, transcription initiation and termination sites etc. Determination of amino acid sequences and protein products, Secondary and tertiary structures of proteins and other properties. Design of specific primers for PCR amplification of DNA and prediction of conditions for PCR. Use of appropriate databases on bio-informatics in problem analysis.

>< Methodology: Lectures and exercises using software designed for DNA and protein analysis.
>< Scheme of evaluation: Continuous assessment and course assignment.
>< Recommended reading:
01. Baxevanis, A. D. and Francis, B. F. (2001). Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. John Wiley & Sons.
02. Gibas, C., Fenton, J. F., Jambeck, P. and Lejenne, L. (2000). Developing Bioinformatics Computer Skills. O’Reilly & Associates.
03. Mount, D. W. and Mount, D. (2002). Bioinformatics: Sequence and Genome Analysis. Cold Spring Harbor Laboratory.

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